Induction of mucosal B-cell memory by intramuscular inoculation of mice with rotavirus.
نویسندگان
چکیده
We investigated the capacity of intramuscular (i.m.) immunization with heterologous-host rotavirus (simian strain RRV) to induce mucosal virus-specific memory B cells in mice. We found that prior i.m. immunization enhanced the magnitude of mucosal virus-specific immunoglobulin A (IgA) production but did not alter the site and timing of induction of virus-specific IgA responses after challenge.
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ورودعنوان ژورنال:
- Journal of virology
دوره 72 4 شماره
صفحات -
تاریخ انتشار 1998